11/21/2023 0 Comments Causes of temporary amnesiaBecause of the implicated loss of declarative memory, ischemia in bilateral hippocampi has been suggested as a possible cause. 9 Past studies have attempted to correlate TGA to vascular risk factors, migraine, and epilepsy, with variable results. 7, 8ĭespite the general acceptance of TGA as a clinical entity, its etiology has yet to be determined. 4 – 6 The average age of onset has ranged between 50–80 years, with an incidence of approximately 5–11 per 100,000 per year. Previous studies on TGA have been inconsistent regarding sex prevalence. ![]() 1 – 3 Though generally self-limited with rare recurrences, this striking presentation has spurred efforts to link TGA to more consequential and treatable conditions. Transient global amnesia (TGA) is an uncommon amnestic syndrome characterized by a combined anterograde and retrograde amnesia of sudden onset. All minority populations showed a lower rate of diagnosis that fell short of statistical significance. Patients with migraines and patients classified as Caucasian had higher odds of being diagnosed with TGA. TGA was associated with lower hospital charges ($14,242 versus $21,319), shorter hospital stays (mean days: 2.49 versus 4.72 ), and routine hospital discharges (91.4% versus 74.5%). The odds of being diagnosed with TGA was lower among African Americans and Hispanics as well as among patients classified as Asian/Other, compared with Caucasians. Similarly, patients with TGA were more likely to have hypertension, precerebral disease, and hyperlipidemia. ![]() Patients with migraines were 5.98 times more likely to also have a diagnosis of TGA compared with patients without migraines. Descriptive and survey logistic regression analyses were conducted and adjusted for influence of comorbidities, demographic characteristics, and hospitalization-related factors. Data were obtained from the Nationwide Inpatient Sample using ICD-9 and procedure codes. The purpose of this article was to explore sex- and race-specific variables and comorbidities associated with transient global amnesia (TGA) using a nationally representative database.
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